Authors
Handbook of
Autoinflammatory
Diseases
About the book
Welcome to the enlightening exploration in the pages of the “Handbook of Autoinflammatory Diseases”, an insightful compilation meticulously curated by the distinguished Prof. Tania Sih and Prof. Leonardo Oliveira Mendonça, with their usual expertise and enthusiasm. In this comprehensive volume, we embark on a captivating journey through the intricate puzzle of autoinflammatory diseases, traversing historical landscapes, genetic complexities and clinical nuances that collectively contribute to our growing understanding of these intriguing conditions.
Summary
1. Immunology, the Science of the Century
2. A Brief Journey Through the History of Autoinflammatory Diseases
3. Differences Between Autoimmune and Autoinflammatory Diseases
4. Immunological Basis of Autoinflammatory Diseases
5. A Practical Approach to the Genetic Diagnosis of Autoinflammatory Diseases
6. PFAPA - General Considerations
7. PFAPA - Treatment
8. Familial Mediterranean Fever
9. Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)
10. A Growing Constellation of NLRP3-Associated Autoinflammation: Cryopyrin-Associated Periodic Syndrome (CAPS)
11. Hyper-IgD Syndrome
12. Deficiency of the Natural Antagonist of the Interleukin-1 (DIRA)
13. Deficiency of the Natural Antagonist Interleukin-36 (DITRA)
14. Autoinflammation with Infantile Enterocolitis (AIFEC) Associated with NLRC4
15. STING-Associated Vasculopathy with Onset in Infancy (SAVI)
16. Proteasome - Associated Autoinflammatory Syndrome (PRAAS)
17. Deficiency of Adenosine Deaminase 2 (DADA2)
18. Aicardi-Goutières Syndrome
19. Immunoregulation Syndrome, Polyendocrinopathy and X-linked Enteropathy (IPEX)
20. CHAI (CTLA4) and LATAIE (LRBA)
21. Autoimmune Lymphoproliferative Syndrome (ALPS)
22. Pyogenic Arthritis, Acne Conglobata and Pyoderma Gangrenosum Syndrome (PAPA)
23. Monogenic Behcet's Disease
24. STAT1 Gain-of-function Disease
25. STAT3 with Gain-of-Function: Early-Onset Multisystem Disease
26. Activated PI3Kδ Syndrome (APDS)
27. CDC42-Related Autoinflammatory Diseases
28. SAMD9L
29. NF-kβ Essential Modulator Deficiency Syndrome (NEMO)
30. Macrophage Activation Syndrome (MAS)
31. Vacuole, E1- Enzyme, X-linked, Autoinflammatory, Somatic Syndrome (VEXAS)
32. Very Early - Onset Inflammatory Bowel Diseases
33. Syndrome of Undifferentiated Recurrent Fever (SURF)
Immunologist and allergist trained at HCFMUSP, with clinical and laboratory fellowship in autoinflammatory and immunodysregulatory diseases at the Istituto Gianina Gaslini in Genoa, Italy. Clinical Immunology and Allergy Professor at UNISA and physician at the outpatient clinic for autoinflammatory diseases at HCFMUSP.
Dr. Leonardo Mendonça
Otorhinolaryngologist Prof of FMUSP and director of the Interamerican Association of Pediatric Otorhinolaryngology - (IAPO)
General Secretary of IAPO
Former President of ISOM (International Society of Otitis Media)
Author of 35 books on pediatric ENT.
Dr. Tania Sih
IAPO
Rua Mato Grosso, 306, Higienópolis, Conj. 1511
São Paulo / SP - CNPJ: 01.557.821/0001-96
Contact: iapo@iapo.org.br